Comparison of Osmotic Resistance, Shape and Transmembrane Potential of Erythrocytes Collected from Healthy and Fed with High Fat-Carbohydrates Diet (HF-CD) Pigs — Protective Effect of Cistus incanus L. Extracts
Sylwia Cyboran-Mikołajczyk , Robert Pasławski , Urszula Pasławska , Kacper Nowak , Michał Płóciennik , Katarzyna Męczarska , Jan Oszmiański , Dorota Bonarska-Kujawa , Paweł Kowalczyk , Magdalena Wawrzyńska
AbstractLong-term high fat-carbohydrates diet (HF-CD) contributes to the formation of irreversible changes in the organism that lead to the emergence of civilization diseases. In this study, the impact of three-month high-fat diet on the physical properties of erythrocytes (RBCs) was studied. Furthermore, the biological activity of Cistus incanus L. extracts, plant known with high pro-health potential, in relation to normal and HF-CD RBCs, was determined. Obtained results have shown that, applied HF-CD modified shape, membrane potential and osmotic resistance of erythrocytes causing changes in membrane lipid composition and the distribution of lipids. The impact of HF-CD on physical properties of RBCs along with atherosclerotic lesions of the artery was visible, despite the lack of statistically significant changes in blood morphology and plasma lipid profile. This suggests that erythrocytes may be good markers of obesity-related diseases. The studies of biological activity of Cistus incanus L. extracts have demonstrated that they may ameliorate the effect of HF-CD on erythrocytes through the membrane-modifying and antioxidant activity.
|Journal series||Materials, ISSN 1996-1944, (N/A 140 pkt)|
|Publication size in sheets||0.65|
|Keywords in English||erythrocytes; fat-carbohydrates diet (HF-CD); Cistus incanus L. extracts; pigs; osmotic resistance|
|License||Journal (articles only); published final; ; with publication|
|Score||= 140.0, 28-04-2021, ArticleFromJournal|
|Publication indicators||= 0; = 0; : 2017 = 1.285; : 2018 = 2.972 (2) - 2018=3.532 (5)|
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