Active surveillance for antibodies confirms circulation of lyssaviruses in Palearctic bats
Veronika Seidlova , Jan Zukal , Jiri Brichta , Nikolay Anisimov , Grzegorz Apoznański , Hana Bandouchova, , Tomáš Bartonička , Hana Berkova , Alexander D. Botvinkin , Tomas Heger , Heliana Dundarova , Tomasz Kokurewicz , Petr Linhart , Oleg L. Orlov , Vladimir Piacek , Primož Presetnik , Alexandra P. Shumkina , Mikhail P. Tiunov , Treml Frantisek , Jiri Pikula
AbstractBackground Palearctic bats host a diversity of lyssaviruses, though not the classical rabies virus (RABV). As surveillance for bat rabies over the Palearctic area covering Central and Eastern Europe and Siberian regions of Russia has been irregular, we lack data on geographic and seasonal patterns of the infection. Results To address this, we undertook serological testing, using non-lethally sampled blood, on 1027 bats of 25 species in Bulgaria, the Czech Republic, Poland, Russia and Slovenia between 2014 and 2018. The indirect enzyme-linked immunosorbent assay (ELISA) detected rabies virus anti-glycoprotein antibodies in 33 bats, giving an overall seroprevalence of 3.2%. Bat species exceeding the seroconversion threshold included Myotis blythii, Myotis gracilis, Myotis petax, Myotis myotis, Murina hilgendorfi, Rhinolophus ferrumequinum and Vespertilio murinus. While Myotis species (84.8%) and adult females (48.5%) dominated in seropositive bats, juveniles of both sexes showed no difference in seroprevalence. Higher numbers tested positive when sampled during the active season (10.5%), as compared with the hibernation period (0.9%). Bat rabies seroprevalence was significantly higher in natural habitats (4.0%) compared with synanthropic roosts (1.2%). Importantly, in 2018, we recorded 73.1% seroprevalence in a cave containing a M. blythii maternity colony in the Altai Krai of Russia. Conclusions Identification of such “hotspots” of non-RABV lyssavirus circulation not only provides important information for public health protection, it can also guide research activities aimed at more in-depth bat rabies studies.
|Journal series||BMC Veterinary Research, ISSN 1746-6148, (N/A 140 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Chiroptera, rabies, blood samples, seroprevalence, Europe,Siberia|
|License||Journal (articles only); published final; ; after publication|
|Score||= 140.0, 21-01-2021, ArticleFromJournal|
|Publication indicators||= 0; : 2018 = 1.026; : 2018 = 1.792 (2) - 2018=2.12 (5)|
|Citation count*||1 (2021-05-07)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.