The impact of environmental stress on Listeria monocytogenes virulence
Ewa Wałecka , Jerzy Molenda , Jacek Bania
AbstractListeria monocytogenes, a significant food-borne pathogen, must defy a variety of conditionsencountered in the food environment and during the infection process. In reaction to adverse condi-tions, the bacteria significantly change their metabolism, inducing a stress response which is mediatedby a range of alternative sigma factors. The extent of the response to stress was shown to vary in theL. monocytogenespopulation. According to recent evidence a majorL. monocytogenesalternativesigma factor, designated sigma B (σB), regulates some virulence genes in response to stress, whichsupports an older hypothesis that stress-resistant strains should be more pathogenic. The induction ofσB-dependent genes may also be important from the point of view of food hygiene. It seems thatstress response activation can paradoxically enhance resistance to agents used in food preservation.Therefore, monitoring the expression ofσB-dependent genes can serve as a useful marker to assessthe innate resistance ofL. monocytogenesstrains. This knowledge will allow the design of newmethods with sequential preservation steps that could inactivate the bacteria without inducing theirstress response.
|Journal series||Polish Journal of Veterinary Sciences, ISSN 1505-1773, e-ISSN 2300-2557, (A 20 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Listeria monocytogenes, sigma B, stress response, virulence|
|License||Journal (articles only); author's original; ; after publication|
|Publication indicators||= 4; = 3; : 2009 = 0.322; : 2009 = 0.435 (2) - 2010=0.556 (5)|
|Citation count*||6 (2020-09-16)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.