Microbial kinetic resolution of aroma compounds using solid-state fermentation
Filip Boratyński , Ewa Szczepańska , Aleksandra Grudniewska , Teresa Olejniczak
AbstractA novel microbial approach to the production of enantiomerically enriched and pure aroma compounds based on kinetic resolution via solid-state fermentation is proposed. Twenty-five filamentous fungi were screened for lipase activity and enantioselective hydrolysis of a volatile racemic ester (1-phenylethyl acetate (1)) and several racemic lactones (trans and cis whisky lactones (4, 5), γ-decalactone (7), δ-decalactone (8), (cis-3a,4,7,7a-tetrahydro-1(3H)-isobenzofuranone) (9)). Solid-state fermentation was conducted with linseed and rapeseed cakes. Kinetic resolution afforded enantiomerically enriched products with high enantiomeric excesses (ee = 82–99%). The results highlight the potential economic value of solid-state fermentation using agroindustrial side-stream feedstocks as an alternative to more expensive processes conducted in submerged fermentation.
|Journal series||Catalysts, ISSN 2073-4344, (A 30 pkt)|
|Publication size in sheets||0.55|
|Keywords in English||aroma compounds; kinetic resolution; solid-state fermentation; agro-industrial side stream; rapeseed cake; linseed cake; lactones; esters|
|Internal identifier||65082; PX-5a991577d5de4609f45f17ad|
|License||Journal (articles only); published final; ; after publication|
|Score||= 30.0, 15-06-2020, ArticleFromJournal|
|Publication indicators||= 5; = 6; : 2018 = 0.912; : 2018 = 3.444 (2) - 2018=3.808 (5)|
|Citation count*||6 (2020-08-04)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.