Effects of Protein-Iron Complex Concentrate Supplementation on Iron Metabolism, Oxidative and Immune Status in Preweaning Calves
Robert Kupczyński , Michał Bednarski , Kinga Śpitalniak-Bajerska , Krystyna Pogoda-Sewerniak
AbstractThe objective of this study was to determine the effects of feeding protein-iron complex (PIC) on productive performance and indicators of iron metabolism, hematology parameters, antioxidant and immune status during first 35 days of a calf’s life.Preparation of the complex involved enzymatic hydrolysis of milk casein (serine protease from Yarrowia lipolytica yeast). Iron chloride was then added to the hydrolyzate and lyophilizate. Calves were divided into treated groups: LFe (low iron dose)10 g/day calf of protein-iron complex, HFe (height iron dose) 20 g/day calf, and control group. Dietary supplements containing the lower dose of concentrate had a significant positive effect on iron metabolism, while the higher dose of concentrate resulted in increase of total iron binding capacity (TIBC), saturation of transferrin and decrease of and unsaturated iron binding capacity (UIBC), which suggest iron overload. Additionally, treatment with the lower dose of iron remarkably increased the antioxidant parameters, mainly total antioxidant (TAS) and glutathione peroxidase activity (GPx). Higher doses of PIC were related to lower total antioxidant status. IgG, IgM, insulin, glucose, TNF? and IGF-1 concentration did not change significantly in either group after supplementation. In practice, the use of protein-iron complex concentrate requires taking into account the iron content in milk replacers and other feedstuffs.
|Journal series||International Journal of Molecular Sciences, ISSN 1422-0067, (A 30 pkt)|
|Publication size in sheets||0.55|
|Keywords in English||iron; calves; protein-iron complex; immunology; antioxidative status|
|ASJC Classification||; ; ; ; ; ; ;|
|Internal identifier||63546; PX-596f0fd5d5dee47afd4803dd; PX-596f1176d5dee47afd480410|
|License||Journal (articles only); published final; ; after publication|
|Score||= 30.0, 09-09-2020, ArticleFromJournal|
|Publication indicators||= 4; = 2; : 2017 = 1.151; : 2017 = 3.687 (2) - 2017=3.878 (5)|
|Citation count*||3 (2020-04-22)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.