Expression of p16 (INK4a), cytokeratin 19, and Ki-67 in canine laryngeal squamous cell carcinoma
Małgorzata Kandefer-Gola , Rafał Ciaputa , Marcin Nowak , Janusz Madej
The study aimed at morphological and immunohistochemical characteristics of laryngeal squamous cell carcinomas and their metastases in canine lymph nodes and lungs. Tissue sections were stained using classical technique with haematoxylin and eosin. In addition, immunohistochemical studies were performed with p16, cytokeratin, and Ki-67 antibodies. An expression of all examined antigens was detected in laryngeal tumours, while in tumour metastases only expression of p16 protein and cytokeratin was demonstrated. The results pointed to higher proliferative potential of the primary tumour than of their metastases.
|Journal series||Bulletin of the Veterinary Institute in Pulawy, ISSN 0042-4870, (A 20 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Cytokeratin, Dog, Ki-67, Laryngeal squamous cell carcinoma, Metastases, P16 (INK4a)|
|Score|| = 20.0, 04-06-2020, ArticleFromJournal|
= 20.0, 04-06-2020, ArticleFromJournal
|Publication indicators||= 1; = 1; : 2013 = 0.365 (2) - 2013=0.379 (5)|
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