Otrzymywanie izomerów sprzężonego kwasu linolowego (CLA)
Natalia Niezgoda , Paweł Mituła , Czesław Wawrzeńczyk
AbstractLinoleic acid was isomerized in (HOCH2)2 or glycerol in presence of KOH or NaOH at 80-160°C to conjugated I (CLA) (yield 99.3%) contg. 9-cis, 11-trans-I (48.5%) and 10-trans, 12-cis-I (48.3%) isomers. The product was esterified with MeOH in presence of H2SO4 to resp. Me esters of (CLA). The isomeric (CLA) esters were sepd. by low-temp. crystn. in AcMe at -75°C to -50°C. The esters were hydrolyzed to pure isomers of (CLA). The chem. structure of the intermediates and products was confirmed by NMR spectroscopy. The optimum conditions for the isomerization and crystn. were established. The isomeric purity of the (CLA) Me esters was 84% and 97%, resp.
|Other language title versions||Preparation of conjugated linoleic acid (CLA) isomers|
|Journal series||Przemysł Chemiczny, ISSN 0033-2496, (A 15 pkt)|
|Publication size in sheets||0.5|
|Publication indicators||= 9; : 2014 = 0.157; : 2011 = 0.414 (2) - 2011=0.296 (5)|
|Citation count*||10 (2020-08-08)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.