Maternal antibodies in young birds
Klaudia Chrząstek , Anna Woźniak-Biel , Alina Wieliczko
Maternal antibodies (matAb) provide protection for newly hatched chicks against pathogens, especially during the first weeks of age before active antibody production occurs. MatAb are transferred from hens . to their offspring via the eggs, across yolk sac membranes into the embryonic bloodstream. The chicken IgY yolk sac receptor (FcRY), a receptor specific for the Fc portion of IgY, is a homolog of the mammalian phospholipase A2 receptor. Biochemical analysis of FcRY demonstrates that IgY binding is pH dependent. The transfer percentages of matAb are varied. These differences in ratios of antibody transfer from hens to : their day-old chicks indicate a variation e.g. among the pathogens, chicken lines. Maternally transferred antibodies may constitute an important addition to the neonate's ability to handle antigens. However, it may also be suppressive if matAb reduce antigen presentation to the newborn resulting ' : in antigen-specific blocking of offspring endogenous immunity.
|Journal series||Medycyna Weterynaryjna, ISSN 0025-8628, (B 10 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||β-glucan, mannoproteins, glukomannans, toxins bounding, antimicrobial activity|
|Publication indicators||= 1; = 1; : 2014 = 0.141; : 2012 = 0.203 (2) - 2015=0.162 (5)|
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