Salt stress-induced invasiveness of major Listeria monocytogenes serotypes
Ewa Wałecka-Zacharska , Katarzyna Kosek-Paszkowska , Jacek Bania , Renata Karpíšková , Tadeusz Stefaniak
AbstractOf the 13 serotypes, 4b serotype strains are responsible for the majority of recorded invasive listeriosis outbreaks, although some recent listeriosis outbreaks have been attributed to strains of serotypes 1/2a and 1/2b. Virulence and response to osmotic stress in 41 Listeria monocytogenes strains representing serotypes 1/2a, 1/2b and 4b was investigated. It was found that serotype 4b and 1/2b strains exhibited highest invasion efficiency and formed largest plaques in HT-29 cell monolayer. Invasiveness in response to 10-min exposure to 0·3moll-1 NaCl was the highest in serotype 4b strains. We demonstrated that 4b serotype L.monocytogenes strains not only have the greatest pathogenic potential but also are the most invasive in response to salt stress. Significance and Impact of the Study: Listeria monocytogenes 4b serotype strains are responsible for the majority of recorded invasive listeriosis outbreaks. We showed that strains of serotype 4b are not only the most virulent L.monocytogenes strains but also have the best capacity to enhance their invasiveness in response to salt stress. Our results suggest possession of effective stress response mechanisms of 4b serotype strains, which may contribute to the high infection potential of this subpopulation. © 2012 The Society for Applied Microbiology.
|Journal series||Letters in Applied Microbiology, ISSN 0266-8254, (A 25 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Invasiveness; Listeria monocytogenes; Osmotic stress; Plaque-forming assay|
|Score|| = 20.0, 25-08-2020, ArticleFromJournal|
= 25.0, 25-08-2020, ArticleFromJournal
|Publication indicators||= 15; = 18; : 2014 = 0.968; : 2013 = 1.749 (2) - 2013=2.069 (5)|
|Citation count*||22 (2020-09-16)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.