Effects of Selected Prebiotics or Synbiotics Administered In Ovo on Lymphocyte Subsets in Bursa of the Fabricius, Thymus, and Spleen in Non-Immunized and Immunized Chicken Broilers
Marianna Szczypka , Agnieszka Suszko-Pawłowska , Maciej Kuczkowski , Michał Gorczykowski , Magdalena Lis , Artur Kowalczyk , Ewa Łukaszewicz , Dominik Poradowski , Iwona Zbyryt , Marek Bednarczyk , Tadeusz Stefaniak
AbstractThe effects of in ovo-delivered prebiotics and synbiotics on the lymphocyte subsets of the lymphoid organs in non-immunized 7-day-old broiler chickens and in non-immunized, sheep red blood cells (SRBC)-immunized, and dextran (DEX)-immunized 21- and 35-day-old birds were studied. The substances were injected on the 12th day of egg incubation: Prebiotic1 group (Pre1) with a solution of inulin, Prebiotic2 group (Pre2) with a solution of Bi2tos (non-digestive transgalacto-oligosaccharides), Synbiotic1 group (Syn1) with inulin and Lactococcus lactis subsp. lactis IBB SL1, and Synbiotic2 group (Syn2) with Bi2tos and Lactococcus lactis subsp. cremoris IBB SC1. In 7-day-old chicks, a decrease in T splenocytes was noticed in all groups. The most pronounced effect in 21- and 35-day-old birds was an increase in TCRγδ+ cells in Syn1 and Syn2 groups. A decrease in bursal B cells was observed in DEX-immunized Pre1 group (21-day-old birds), and in the Syn1 group in non-immunized and SRBC-immunized 35-day-old birds. An increase in double-positive lymphocytes was observed in Pre1 (35-day-old birds) and Pre2 (immunized 21-day-old birds) groups. In Pre1 and Syn1 groups (21- and 35-day-old), an increase in B splenocytes and a decrease in T splenocytes were observed. We concluded that Syn1 was the most effective in the stimulation of the chicken immune system.
|Journal series||Animals, ISSN 2076-2615, e-ISSN 2076-2615, (N/A 100 pkt)|
|Publication size in sheets||0.9|
|Keywords in English||prebiotics; synbiotics; lymphocyte subsets; broiler|
|License||Journal (articles only); published final; ; with publication|
|Score||= 100.0, 06-05-2021, ArticleFromJournal|
|Publication indicators||= 0; = 0; : 2018 = 1.148; : 2019 = 2.323 (2)|
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