Synthesis, Cytotoxicity Assessment and Optical Properties Characterization of Colloidal GdPO4:Mn2+, Eu3+ for High Sensitivity Luminescent Nanothermometers Operating in the Physiological Temperature Range
Kamila Maciejewska , Błażej Poźniak , Marta Tikhomirov , Adrianna Kobylińska , Łukasz Marciniak
AbstractHerein, a novel synthesis method of colloidal GdPO4:Mn2+,Eu3+ nanoparticles for luminescent nanothermometry is proposed. XRD, TEM, DLS, and zeta potential measurements confirmed the crystallographic purity and reproducible morphology of the obtained nanoparticles. The spectroscopic properties of GdPO4:Mn2+,Eu3+ with different amounts of Mn2+ and Eu3+ were analyzed in a physiological temperature range. It was found that GdPO4:1%Eu3+,10%Mn2+ nanoparticles revealed extraordinary performance for noncontact temperature sensing with relative sensitivity SR = 8.88%/°C at 32 °C. Furthermore, the biocompatibility and safety of GdPO4:15%Mn2+,1%Eu3+ was confirmed by cytotoxicity studies. These results indicated that colloidal GdPO4 doped with Mn2+ and Eu3+ is a very promising candidate as a luminescent nanothermometer for in vitro applications.
|Journal series||Nanomaterials, ISSN 2079-4991, (N/A 70 pkt)|
|Publication size in sheets||0.7|
|Keywords in English||cytotoxicity, luminescent nanothermometers, nanoparticles, optical properties, synthesis, transition metals|
|License||Journal (articles only); published final; ; with publication|
|Score||= 70.0, 15-09-2020, ArticleFromJournal|
|Publication indicators||= 2; = 1; : 2018 = 4.034 (2) - 2018=4.358 (5)|
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