Changes in the Secretion of Anti-Inflammatory Cytokines and Acute-Phase Proteins in the Uterus after Artificial Insemination in the Mare
Katarzyna Wojtysiak , Wojciech Ryszka , Tadeusz Stefaniak , Jarosław Król , Roland Kozdrowski
AbstractThe objective of the study was to evaluate the concentrations of interleukin-1 receptor antagonist (IL-1RA), interleukin-10 (IL-10), serum amyloid A (SAA) and haptoglobin (Hp) in uterine lavage fluid before and after artificial insemination (AI). Based on ultrasound examination, mares were divided into: Group 1 (n = 9), no fluid was detected in the uterus during estrus and 7 h after AI; Group 2 (n = 8), no fluid was detected in the uterus during estrus but 7 h after AI fluid was detected in the uterus; Group 3 (n = 8), fluid was detected in the uterus during estrus and also 7 h after AI. In all groups of mares, a significant increase in polymorphonuclear cells (PMN) and a significant increase in IL-1RA and SAA were recorded 7 h after AI. The obtained results show that, regardless of the status of the mare before AI, the endometrial response characterized by PMN influx, and SAA, Hp, IL-1RA and IL-10 production, is similar. The presence of intrauterine fluid during estrus is not connected with PMN influx but can impact uterine IL-1RA production at this time.
|Journal series||Animals, ISSN 2076-2615, e-ISSN 2076-2615, (N/A 100 pkt)|
|Publication size in sheets||0.55|
|Keywords in English||mare; artificial insemination; endometritis; cytokines; acute-phase proteins|
|License||Journal (articles only); published final; ; with publication|
|Score||= 100.0, 10-05-2021, ArticleFromJournal|
|Publication indicators||= 0; = 0; : 2018 = 1.148; : 2019 = 2.323 (2)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.